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Tryptophan metabolism in central nervous system diseases: Pathophysiology and potential therapeutic strategies

Keywords Non-alcoholic fatty liver disease, Liver cancer genome-wide association studies, Single nucleotide polymorphisms, Risk analysis Introduction Non-alcoholic fatty liver disease (NAFLD) is a non-communicable disease associated with at least a quarter of the worlds population

Frana MER, Ramos RKLG, Oliveira WH, Duarte-Silva E, Arajo SMR, Los DB, et al

Conversely, our observation of elevated GSSG in cells lacking MPC1 (Figure 8B) suggests that, at a minimum, GSSG is not incompatible with diminished sensitivity to NAFLD